Applications of MALDI-TOF mass spectrometry in clinical diagnostic microbiology
نویسندگان
چکیده
منابع مشابه
Application of MALDI-TOF mass spectrometry in clinical diagnostic microbiology.
Matrix-assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) has recently emerged as a powerful technique for identification of microorganisms, changing the workflow of well-established laboratories so that its impact on microbiological diagnostics has been unparalleled. In comparison with conventional identification methods that rely on biochemical tests and requ...
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Clinical microbiology laboratories today operate with the use of a blend of highand low-technology procedures. Despite huge steps forward in diagnostic methods based on nucleic acid amplification, clinical microbiology laboratories still rely heavily on culturing bacteria and fungi for diagnostic purposes. This process is typically done on solid (e.g., blood agar) and occasionally in liquid (i....
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Matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI-TOFMS) is used to obtain fast and accurate determinations of molecular mass, but quantitative determinations are generally made by other techniques. In this study we illustrate the practical utility of automated MALDI-TOFMS as a tool for quantifying a diverse array of biomolecules covering an extensive molecular...
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ژورنال
عنوان ژورنال: FEMS Microbiology Reviews
سال: 2012
ISSN: 1574-6976
DOI: 10.1111/j.1574-6976.2011.00298.x